Hepatitis Treatment Drugs

Additional Information:

• Item Code: 29602CET214002

• Safe usage
• Highly effective
• Precise composition

• Entavir is used to treat a chronic viral infection of the liver (hepatitis B).
• It works by slowing the growth of the virus. Entecavir is a nucleoside analog-type (NRTI) medication.
• Entecavir is not a cure for hepatitis B and does not prevent the spread of hepatitis B to others through contact or blood/body fluid contamination (e.g., sharing used needles).
• A series of shots (vaccine) are available to protect uninfected people from hepatitis B virus.

Additional Information:

• Item Code: CET-957197509

• Hepcinat (Sofosbuvir) is a breakthrough treatment for Hepatitis C infections. Its mechanism of action involves inhibiting the enzyme which is necessary for the virus if it is to multiply.
• A complete cure may even be possible. Chronic hepatitis C is a serious infection of the liver which occurs following an infection with the hepatitis C virus. Upon reaching the cells of the liver, the virus begins to multiply, which it achieves by means of copying its DNA and RNA.
• This medicine is known as a nucleotide polymerase inhibitor, and it works directly on the virus itself.After oral administration, it undergoes a process of intracellular metabolism in which it is converted to its active form. It subsequently starts to work, whereupon it actively targets the enzyme that is used by the virus to produce RNA chains (HCV NS5B RNA-dependent RNA polymerase). This can help to stop viral multiplication. Treatment of genotypes 1, 2, 3 and 4 is possible with this medicine, however it is always used in combination with other medications and never on its own.
• Dosage and AdministrationHepcinat (Sofosbuvir) film coated tablets each contain 400mg of the main ingredient. The dosage schedule must be individualized by the physician in charge of treatment, and will vary according to the viral genotype that is being treated. Adult patients will usually be directed by their physician to take 1 tablet per day, and it can be administered alongside a meal or else without food.Those suffering from GT1 or GT4 (genotype 1 or 4) may be ordered by the physician to take it alongside ribavirin and peginterferon alfa, with treatment lasting for a period of 12 weeks. In contrast to this, GT2 (genotype 2) is usually treated for 12 weeks, and it is taken alongside ribavirin. GT3 (genotype 3) requires 24 weeks of treatment in combination with ribavirin. Patients must only take it according to the instructions provided to them by the physician in charge of treatment.
• Side effects Remember that it will be necessary to inform your physician of any side effects that affect you as a result of taking Hepcinat (Sofosbuvir) tablets.

• Headache
• A tired feeling
• A decrease in appetite
• Problems sleeping properly
• Itchy feeling which is mild in nature
• It will be necessary to go to the emergency room straight away or to immediately see a physician if you suffer from behavior which is significantly different to before, feeling severely weakened, a pale appearance, swollen gums, sores occurring in the mouth or any other serious adverse events which have not been referenced here.

Additional Information:

• Item Code: 4150004NHT4200004

• Adefovir is used to treat chronic (long-term) hepatitis B infection (swelling of the liver caused by a virus) in patients who have symptoms of the disease. Adefovir is in a class of medications called nucleotide analogs. It works by decreasing the amount of hepatitis B virus (HBV) in the body. Adefovir will not cure hepatitis B and may not prevent complications of chronic hepatitis B such as cirrhosis of the liver or liver cancer. Adefovir may not prevent the spread of hepatitis B to other people. Adefovir comes as a tablet to take by mouth. It is usually taken once a day with or without food.
• Take adefovir at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take adefovir exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Additional Information:

• Item Code: CAT-654067006

Uses:
SoviHep 400mg (Sofosbuvir) is a nucleotide analog inhibitor of hepatitis C virus NS5B polymerase—the key enzyme mediating HCV RNA replication. Sofosbuvir is a prodrug and after ingestion it is rapidly converted to GS-331007, the predominant circulating drug that accounts for greater than 90% of the systemically active drug. This triphosphate compound mimics the natural cellular uridine nucleotide and is incorporated by the HCV RNA polymerase into the elongating RNA primer strand, resulting in chain termination. The active form GS-461203 targets the NS5B catalytic site and acts as a non-obligate chain terminator. The active compound (GS-461203) does not inhibit host DNA polymerases, RNA polymerases, or mitochondrial RNA polymerase.SoviHep 400mg is available as a 400 mg tablet. The recommended dose of sofosbuvir is 400 mg taken orally once daily, with or without food. The 400 mg dose of sofosbuvir should be used, regardless of the patient's genotype and prior hepatitis C treatment experience. No dose adjustment is needed for mild-to-moderate renal impairment or with mild, moderate, or severe hepatic impairment. SoviHep 400mg has been very well-tolerated in clinical trial. The most common adverse effects observed with sofosbuvir, when used in combination with ribavirin, have been fatigue and headache. Sofosbuvir is pregnancy category B.The major concern with drug interactions exists with medications that are strong inducers of intestinal P-gp, such as rifampin and St. John's wort, since these compounds may significantly lower sofosbuvir and GS-331007 levels. The coadministration of sofosbuvir with the following medications is not recommended because these medications may significantly lower sofosbuvir levels:

• Anticonvulsants: carbamazepine, oxycarbazepine, and phenytoin
• Antimycobacterials: rifampin, rifapentine
• Herbal Supplements: St. John's wort (Hypericumperforatum)
• HIV Protease Inhibitiors: tipranavir.

Peginterferon alfa-2a is used to treat chronic hepatitis B or C.

Peginterferon alfa-2a is often used together with another medication called ribavirin

Uses:
Resof contains Sofosbuvir.

Sofosbuvir is used for Treating chronic hepatitis C virus (HCV) infection in certain patients. It must be used with ribavirin or in combination with peginterferon alfa and ribavirin.

Sofosbuvir is an HCV nucleotide analog polymerase inhibitor. It reduces the amount of HCV in the body by preventing the spread of the HCV within the body.